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If the recommended starting dosage is [see Use in Specific Populations (8.6)]: Not tolerated, discontinue IMCIVREE

The peptides biological activity stems from its interaction with multiple growth factor receptors, particularly those involved in angiogenesis and extracellular matrix remodelling

Often, alternative treatments exist that dont involve appetite suppression

In the Phase 3 database, the mean HbA1c increase was approximately 0.1 to 0.2 percent at 52 weeks, clinically minor for most subjects but relevant for anyone with pre-existing insulin resistance or type 2 diabetes

Rush CJ, Berry C, Oldroyd KG, Rocchiccioli JP, Lindsay MM, Touyz RM, et al

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